HIV Infection And Neonatal Outcomes In Pregnant Women Living With Hiv In Iran: A Systematic Review
Keywords:
Acquired Immune Deficiency Syndrome Virus, pregnancy outcome, infectious, epidemiology, Iran.Abstract
Background
Pregnant women worldwide face a significant public health problem caused by HIV infection. In addition to the risk of mother-to-child transmission, it can result in significant complications and detrimental pregnancy and neonatal outcomes. No comprehensive evidence is available to measure the neonatal outcomes of HIV infection in pregnant women in Iran. This study aimed to assess neonatal outcomes of HIV infection in pregnant women in Iran.
Methods
The search for international databases, including PubMed, Scopus, ISI, and Embase, as well as all national databases, was done systematically until September 25th, 2024. The inclusion criteria encompassed any records reporting neonatal outcomes among pregnant women in Iran. The study outcomes included any neonatal implications related to HIV infection in pregnant women.
Results
A total of seven studies with participating 497 pregnant women living with HIV were identified. Abortion was the most common adverse pregnancy outcome. The proportion of newborns with HIV infection varied from 0% to 25.7%. The live birth rate exceeded 95% in most studies. Prophylaxis has been initiated for all newborns. Infant growth was within the normal range for the majority of infants.
Conclusion
Adverse neonatal outcomes among pregnant mothers with AIDS in Iran are quite low, and most of them receive care.
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Copyright (c) 2025 Zhaleh Behrouzi, Dr. Shamsi Abbasalizadeh, Zahra Zeinali

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