Idiopathic Pulmonary Fibrosis (IPF) Treatment and Prognosis: A Comprehensive Review
DOI:
https://doi.org/10.63278/1360Keywords:
idiopathic pulmonary fibrosis, prognostic factors, treatment, monitoring, follow-upAbstract
Idiopathic pulmonary fibrosis (IPF), a devastating progressive interstitial lung disease (ILD) with no known cause, is the most common and deadly of the idiopathic interstitial pneumonias. With a median survival of 3–5 years following diagnosis, IPF is characterized by a progressive decline in lung function and quality of life in most patients. Prognostic factors recognized classically that influence mortality include functional, clinical and radiological parameters. However, in recent years, there has also been progress in the knowledge of genetic factors and biomarkers that may be useful in the prognostic evaluation of these patients. On the other hand, the monitoring of the disease throughout its evolution is key to improving the prognosis of the patients, as it allows for taking therapeutic measures based on this evolution, even early remission for lung transplantation. This article reviews the main prognostic factors of the disease, as well as the most useful way to monitor the disease follow-up.
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Copyright (c) 2025 Mohammed Ali Alshahrani, Mosa Theeban Al Garni, Yousef Ali Alzamil, Khaled Jobran Alshahrani, Mohammed Saad Alahmari, Abdullah Ahmed Albeair, Mohammed Abdullah Alamri, Eyad Hassan Jaber Alkadi, Mohammed Moshabbab Alahmari

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