Cutaneous Hamartoma in a Paediatric Patient: A Case Report on Accessory Eyelashes and Auricular Lesion
DOI:
https://doi.org/10.63278/10.63278/mme.v31.1Abstract
Background: Cutaneous hamartomas are rare, benign congenital malformations involving the abnormal proliferation of native tissue components in an irregular arrangement. They can present in various anatomical regions, often posing diagnostic challenges. Accessory eyelashes and auricular lesions are uncommon manifestations of cutaneous hamartomas, necessitating careful evaluation to differentiate them from other nevoid or choristomatous conditions.
Case Presentation: We report the case of a 4-year-old female with no significant medical history, presenting with a pedunculated lesion measuring 0.5 × 0.5 cm on the left outer canthus of the eye, along with a smaller lesion on the right ear. The lesions were asymptomatic, showing no erythema or discharge. The patient underwent surgical excision of both lesions under general anesthesia. The left accessory eyelash lesion was removed using an elliptical incision, while the right auricular lesion was excised and repaired with subcutaneous sutures. Histopathological examination of the left canthal lesion revealed large hair follicles intermixed with sweat glands and fatty tissue in the dermis, confirming the diagnosis of a cutaneous hamartoma. The findings excluded differential diagnoses such as distichiasis or choristoma.
Conclusion: This case highlights a rare presentation of cutaneous hamartoma involving accessory eyelashes and an auricular lesion in a pediatric patient. Surgical excision, coupled with histopathological analysis, remains the cornerstone for accurate diagnosis and effective management. Awareness of such atypical presentations is essential for early intervention, ensuring favorable cosmetic and functional outcomes. Further studies are needed to explore the pathogenesis and optimal management strategies for cutaneous hamartomas.
References
Mills O., Thomas L.B. Basaloid follicular hamartoma. Arch Pathol Lab Med. 2010;1(8):1215–1219.
Del Barrio-Diaz P, Meza-Romero R, González S, Vera-Kellet C. Cutaneous inflammation as a marker of malignant transformation in a patient with linear unilateral basaloid follicular hamartoma. Indian J Dermatol Venereol Leprol [Internet]. 85(3):287–290.
Brown A.C., Crounse R.G., Winkelmann R.K. Generalized hair-follicle hamartoma, associated with alopecia, aminoacidura, and myasthenia gravis. Arch Dermatol. 1969;99:478–493.
Ridley C.M., Smith N. Generalized hair follicle hamartoma associated with alopecia and myasthenia gravis: report of a second case. Clin Exp Dermatol. 1981;6(3):283–289.
Mehregan A.H., Baker S. Basaloid follicular hamartoma: three cases with localized and systematized unilateral lesions. J Cutan Pathol. 1985;12:55–65.
Weltfriend S., David M., Ginzburg A. Generalized hair follicle hamartoma: the third case report in association with myasthenia gravis. Am J Dermatopathol. 1987;9:428–432.
Akasaka T., Kon S., Mihm M.C., Jr. Multiple basaloid cell hamartoma with alopecia and autoimmune disease (systemic lupus erythema-tosus) J Dermatol. 1996;23:821–824.
Jakobiec F.A., Zakka F.R., Kim N. Basaloid follicular hamartoma of the eyelid. Ophthalmic Plast Reconstr Surg. 2012;28(5)
Uyar B., Sivrikoz O.N., Sacar H. Basaloid follicular hamartoma on the upper eyelid. Postep dermatologii i Alergol. 2015;32(3):221–224.
Ramos-Ceballos F.I., Pashaei S., Kincannon J.M., Morgan M.B., Smoller B.R. Bcl-2, CD34 and CD10 expression in basaloid follicular hamartoma, vellus hair hamartoma and neurofollicular hamartoma demonstrate full follicular differentiation. J Cutan Pathol. 2008;35(5):477–483.
Naeyaert J.M., Pauwels C., Geerts M.L., Verplancke P. CD-34 and Ki-67 staining patterns of basaloid follicular hamartoma are different from those in fibroepithelioma of Pinkus and other variants of basal cell carcinoma. J Cutan Pathol. 2001;28(10):538–541.
Jedrzynski N, Plum W, Tran AQ, Tooley AA, Dowlatshahi M, Kazim M. Basaloid follicular hamartoma of the eyelid in a pediatric patient. American Journal of Ophthalmology Case Reports. 2020 Sep 1;19:100855.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Sabah Alotaibi, Mohammed Sawabi, Mutlaq Althobaiti

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their published articles online (e.g., in institutional repositories or on their website, social networks like ResearchGate or Academia), as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

Except where otherwise noted, the content on this site is licensed under a Creative Commons Attribution 4.0 International License.



According to the